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Sculptra poly-L-lastic acid (2 vials) SCULPTRA®

Booster effect for natural collagen formation Visible skin aging is closely related to the gradual loss of collagen in the skin.

With SCULPTRA® you declare war on wrinkles! Sculptra stimulates the formation of new collagen fibers. Through a treatment with Sculptra, your face regains the elasticity of earlier years step by step and the skin appears youthfully firm again. During treatment with SCULPTRA, poly-L-lactic acid is injected into the skin. This stimulates the regeneration of endogenous collagen through the patient’s connective tissue cells. This results in a recovery of lost volume. The connective tissue regains its elasticity and the signs of facial aging are corrected. SCULPTRA is suitable for adding volume to sunken areas, particularly to correct skin depressions such as lines, wrinkles or scars and to treat general signs of aging. SCULPTRA is also used for large-scale volume correction in the event of loss of subcutaneous fat tissue (lipoatrophy). The visible build-up effect of Sculptra lasts up to 2 years High patient satisfaction with 80% after 2 years 81% of patients (86% of investigators) confirm an overall improvement after 2 years Good tolerability within the 25-month study period “Rejuvenation effect” with long durability By building up the body’s own connective tissue, entire areas of the face can be given back their youthful elasticity. SCULPTRA injections are suitable for both individual, deep wrinkles and larger areas of sagging skin (liquid lift): cheekbone hollow cheeks nasolabial fold mouth corner crease chin jawline temples SCULPTRA is not an immediate wrinkle filler such as hyaluronic acid or autologous fat. The poly-L-lactic acid stimulates the regeneration of collagen. The final result of the treatment is therefore only visible after several months. However, a first assessment by the doctor is possible 4 to 6 weeks after the first injection. One to three treatments with SCULPTRA are necessary until the desired result is achieved. The “booster effect” lasts for up to two years. Due to the natural aging process, the skin can then lose some of its elasticity. After that, a refresher treatment is often enough for a long time. Tolerability of SCULPTRA Poly-L-lactic acid as the main ingredient in SCULPTRA® is a well-documented and bio-engineered ingredient. Due to its nature, it is generally very well tolerated. Allergies and intolerances are unlikely. Treatment with SCULPTRA can therefore be started immediately by a doctor. Sculptra is a unique injectable volumizer that stimulates the body’s own production of collagen. From its introduction in 1999 to date, a whole series of clinical studies have been carried out with Sculptra, which confirm the high effectiveness and safety of the product in its use. Sculptra was originally introduced as a volume building material for HIV-associated facial lipoatrophy. A lot of experience has been gained over the years and the treatment parameters have been adjusted accordingly. As technical aspects have also evolved, Sculptra has proven to be safe and effective, with predictable and reproducible results. Subtle, natural-looking and long-lasting results can be achieved with just a reasonable amount and using the emerging pathophysiological principles of facial aging.

1. Radiant naturalness The skin’s own natural collagen structure: Stimulated by the injection of Sculptra into the deep layers of the skin, the body forms new collagen (connective tissue) itself.

2. Absolute discretion Gradual visual effects: smoothing and tightening become visible after about 6 weeks and reach their maximum harmonious effect after about 3 to 4 months. As with other processes, the organism needs this time to regenerate connective tissue naturally.

3. New possibilities through a unique increase in clamping force With Sculptra, your doctor can offer you more than just filling up wrinkles. By building up the body’s own connective tissue, it is possible to give entire areas of the face back their youthful elasticity and lost contours (so-called liquid lifting). A good assessment of the initial treatment by the doctor is already possible 6 weeks after the first injection. You should then decide together with your doctor whether further treatment should increase the effect or whether you want to treat other areas of your face with Sculptra. Most Sculptra patients are very satisfied with the results after 2 to 3 treatments.

4. Long Effect –

up to 2 years The build-up effect lasts up to 2 years. Due to the natural aging process, the skin can then lose its elasticity and the treatment may need to be refreshed. Sculptra- efficient and innovative treatment option for men The image of men has changed significantly in our society in recent years. Decades ago, the use of cosmetic care products and the implementation of aesthetic treatments for men was a taboo subject. Today, on the other hand, both men and women attach great importance to a well-groomed, fresh, youthful appearance. A sporty, dynamic and attractive appearance is desired. In the professional world, this is often equated with success, dynamism and strength. But not only in the business world an attractive appearance pays off. In the private sphere, too, a positive charisma and satisfaction with one’s own appearance is an important factor for personal well-being and the associated self-confidence. For this reason, more and more men decide to improve their appearance with a modern method of wrinkle therapy. When looking for a suitable method, men in particular have very high demands: the treatment should be individually tailored to their type, be quick and, if possible, without downtime, and deliver both effective and long-lasting results. Efficiency is required! Added to this is the desire for discretion. The personal environment should not notice that an aesthetic treatment has been carried out. Sculptra offers the modern man: minimally invasive treatment. After the treatment, men are socially acceptable again. Causal effect through the skin’s own natural collagen structure: Stimulated by the injection of Sculptra into the deep layers of the skin, the body itself forms new collagen (connective tissue). Wrinkles are smoothed over the long term through the body’s own collagen build-up. Absolute discretion through gradual optical effects: smoothing and tightening become visible after about 6 weeks and reach their maximum harmonious effect after about 3 to 4 months. As with other processes, the organism needs this time to regenerate connective tissue naturally. Long-term effect – up to 2 years: The build-up effect lasts up to 2 years. Sculptra – the efficient, proven option for tightening facial skin, maintaining or restoring youthful facial contours and facial proportions. aging process of the face Influence of the aging process on facial features Change in proportions and loss of contour due to loss of elasticity over the entire area Under the influence of external (UV light, stress, nicotine, …) and internal factors (natural aging process, hereditary predisposition) there are a number of changes in skin tissue, muscles and bone structure. The supporting and elastic fiber network of our connective tissue essentially consists of collagen fibers. This ensures youthful proportions and the elastic tension of the skin. (see also structure of the skin) With age, the skin loses elasticity due to the reduction in the body’s own collagen production and increasingly sags. Fat pads are redistributed. Due to gravity, they migrate to the lower half of the face. There are also degenerative changes in the muscles and bone structure. This not only leads to the formation of fine lines and wrinkles, but also to a change in facial proportions and a blurring of the once clear youthful contour. (see also The skin in old age) effects of the aging process With age, facial skin is no longer so firm, proportions change and once clear, firm contours become blurred. Sculptra to restore youthful facial features When Sculptra, the injectable poly-L-lactic acid, is injected into the skin, it stimulates the production of new collagen. The new collagen creates volume and corrects the signs of facial aging The effect of Sculptra improves: • the elasticity of the fabric, • the firmness of the skin, • the density of the fabric, • the contours of the face and thus ensures a long-lasting, natural-looking and youthful appearance. SCULPTRA is injected at a dilution of 9 ml (7 ml sterile water for injections and 2 ml lidocaine). Superficial injection is contraindicated; SCULPTRA should only be injected subcutaneously or supraperiosteally Reconstitution: the mixed product must be ‘rested’ for at least 24-48 hours to allow a homogeneous solution No injection in hyperdynamic areas such as: forehead, crow’s feet, corners of the mouth, red lips, upper lip wrinkles and tear trough Composition:

One vial of dry substance contains:

150.0 mg poly-L-lactic acid,

90mg sodium carboxymethyl cellulose,

127.5 mg pyrogen-free mannitol

Package content:

2 vails x 5ml

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